Overview of the preparation Celebrex

Celebrex belongs to the group of non-steroidal anti-inflammatory drugs. It has an analgesic, antipyretic and anti-inflammatory effect, which makes it possible to use the drug with toothache. Its core active agent is celecoxib, which inhibits the activity of COX 2. As auxiliary ingredients, monohydrate lactose, sodium lauryl sulfate, sodium croscarmellose, magnesium stearate, polyvidone K30, gelatin and titanium dioxide have been included. The product has analgesic, antipyretic and anti-inflammatory effect on the body.

Celebrex provokes the formation of gastroduodenal ulcers and other complications to a lesser extent than other drugs belonging to the group of non-steroidal anti-inflammatory drugs (such as acetylsalicylic acid, ibuprofen and naproxen). Also, studies show that its daily dose does not affect the clotting capacity and the function of platelets.

Indications for Use

In general, Celebrex can be administered when some of the following conditions or symptoms are present:

  1. Osteoarthritis;
  2. Rheumatoid arthritis;
  3. A pain syndrome of different etiology (including post-surgery pains, toothache, menstrual, bone or muscle pains).


There are also some contraindications, when using this drug is considered undesired or even impossible. The major ones to mention are:

  • Is celebrex good for toothache photoPresence of allergic reactions in the patient’s history (urticaria, bronchospasm), which are related to the intake of the acetylsalicylic acid and other non-steroidal anti-inflammatory drugs.
  • A severe kidney dysfunction.
  • A severe liver dysfunction.
  • The third pregnancy trimester.
  • The period of lactation (breastfeeding)
  • Hypersensitivity to sulfonamides.
  • Hypersensitivity to some ingredients of the product.

It should be kept in mind that the active substance can penetrate to the breast milk, which is potentially dangerous for the baby. This is why, if taking a course of treatment with this medication is really needed, you should give up breastfeeding. So make sure the expected benefits can make up the risks for your baby.

After aortocoronary bypass surgery, Celebrex should not be used too. If any of the abovementioned is your case, ask yourself:  ‘Is celebrex good for toothache in my specific situation?’ Please, note also that the effect of this medicine on children and teenagers under 18 years old have not been studied.

This drug can also affect your capacity for driving and performing activities that require staying focused. To take the right decision regarding the administration of the medicine, the patient’s individual reactions to its ingredients are to be investigated first.

The Mode of Administration and Dosage

If not specified otherwise by your doctor, you can refer to these guidelines to determine the daily Celebrex dosage for toothache and other conditions:

  1. Celebrex dosage for toothache photoWith osteoarthritis, adults can take 200 mg of Celebrex daily. In clinical tests, daily dosages of up to 400 mg were used.
  2. With rheumatoid arthritis, 200 to 400 mg per day should be taken divided into two intakes.
  3. With pain syndrome, a recommended single dose is about 100-200 mg. If the repetition is needed, make sure the interval between the intakes is at least 4 to 6 hours. The maximum daily dose in this case should not exceed 400 mg.
  4. Celebrex dosage for toothache or acute pain of another nature should stay within the recommended initial dose of 400 mg. Then, if necessary, the patient can take another 200 mg. However, the total dose for the first day should not exceed 600 mg. For the following days, it can vary between 200 and 400 mg.

Side Effects

Does Celebrex work for toothaches? Yes, indeed. On the other hand, people choosing this remedy should be aware of possible side effects too. Below, the major ones are discussed.

  • As for the digestive system, the patients occasionally report abdominal pain, diarrhea, indigestion; more rarely – nausea, vomiting, heartburn, anorexia. If high doses are used for a long time, bleeding, constipation, flatulence and mucous membrane ulcers in the gastrointestinal tract may occur.
  • As for the central nervous system and the peripheral nervous system, the complaints may refer to the headache, nausea, drowsiness or insomnia, blurred vision, depression, agitation, confusion, anxiety, hallucinations, partial loss of hearing or tinnitus.
  • As for the respiratory system, sore throat, cough, dyspnea and bronchospasm are reported in rare cases.
  • As for the genitourinary tract, the kidney deficiency and edema syndrome can occur occasionally.
  • As for the cardiovascular system, agranulocytosis, anemia, leucopenia and thrombocytopenia are the threat.
  • Such allergic reactions as bullous skin rash, angioedema, bronchospasm, anaphylaxis, vasculitis, erythema multiforme and Stevens-Johnson syndrome are sometimes reported too.
  • Such reactions as alopecia, hypersweating and epistaxis cannot be excluded in some cases. Agranulocytosis, anemia, leucopenia and thrombocytopenia, while rather rare manifestations, should be considered too.

Other Considerations

You should better look for another remedy for toothache if there is peptic ulcer of the stomach or duodenum, ulcerative colitis, heart failure, edematous syndrome or hypertension in your medical history.

How Celebrex interacts with other drugs should be considered too. The product is compatible with low dosages of acetylsalicylic acid. No clinically significant interaction of Celebrex with ketoconazole, lithium-containing preparations and methotrexate were detected.

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